Movement Disorders (revue)

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Impact of bilateral pallidal stimulation on DYT1‐generalized dystonia in Japanese patients

Identifieur interne : 003390 ( Main/Exploration ); précédent : 003389; suivant : 003391

Impact of bilateral pallidal stimulation on DYT1‐generalized dystonia in Japanese patients

Auteurs : Satoshi Goto [Japon] ; Kazumichi Yamada [Japon] ; Hideki Shimazu [Japon] ; Nagako Murase [Japon] ; Kazuhito Matsuzaki [Japon] ; Tetsuya Tamura [Japon] ; Shinji Nagahiro [Japon] ; Jun-Ichi Kuratsu [Japon] ; Ryuji Kaji [Japon]

Source :

RBID : ISTEX:462D9BBBA79B6587FA83703CBABC59E6F4F08D8F

Descripteurs français

English descriptors

Abstract

Early‐onset generalized dystonia attributable to a DYT1 gene mutation is a hyperkinetic movement disorder that responds poorly to pharmacotherapy. In this video brief, we show that continuous bilateral stimulation of the globus pallidus internus produced sustained and marked improvements in the motor symptoms and functional disabilities of Japanese patients with DYT1‐generalized dystonia. © 2006 Movement Disorder Society

Url:
DOI: 10.1002/mds.21021


Affiliations:


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Le document en format XML

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<term>Adolescent</term>
<term>Adult</term>
<term>Child</term>
<term>Chromosome Deletion</term>
<term>DYT1 gene mutation</term>
<term>Deep Brain Stimulation (methods)</term>
<term>Disability Evaluation</term>
<term>Dominance, Cerebral (physiology)</term>
<term>Dystonia</term>
<term>Dystonia (genetics)</term>
<term>Dystonia (physiopathology)</term>
<term>Dystonia (therapy)</term>
<term>Electrodes, Implanted</term>
<term>Follow-Up Studies</term>
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<term>Humans</term>
<term>Hyperkinesis (genetics)</term>
<term>Hyperkinesis (physiopathology)</term>
<term>Hyperkinesis (therapy)</term>
<term>Japan</term>
<term>Japanese</term>
<term>Male</term>
<term>Molecular Chaperones (genetics)</term>
<term>Mutation</term>
<term>Nervous system diseases</term>
<term>Trinucleotide Repeats</term>
<term>generalized dystonia</term>
<term>pallidal stimulation</term>
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<term>Globus Pallidus</term>
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<div type="abstract" xml:lang="en">Early‐onset generalized dystonia attributable to a DYT1 gene mutation is a hyperkinetic movement disorder that responds poorly to pharmacotherapy. In this video brief, we show that continuous bilateral stimulation of the globus pallidus internus produced sustained and marked improvements in the motor symptoms and functional disabilities of Japanese patients with DYT1‐generalized dystonia. © 2006 Movement Disorder Society</div>
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<name sortKey="Goto, Satoshi" sort="Goto, Satoshi" uniqKey="Goto S" first="Satoshi" last="Goto">Satoshi Goto</name>
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<name sortKey="Kuratsu, Jun Chi" sort="Kuratsu, Jun Chi" uniqKey="Kuratsu J" first="Jun-Ichi" last="Kuratsu">Jun-Ichi Kuratsu</name>
<name sortKey="Matsuzaki, Kazuhito" sort="Matsuzaki, Kazuhito" uniqKey="Matsuzaki K" first="Kazuhito" last="Matsuzaki">Kazuhito Matsuzaki</name>
<name sortKey="Murase, Nagako" sort="Murase, Nagako" uniqKey="Murase N" first="Nagako" last="Murase">Nagako Murase</name>
<name sortKey="Nagahiro, Shinji" sort="Nagahiro, Shinji" uniqKey="Nagahiro S" first="Shinji" last="Nagahiro">Shinji Nagahiro</name>
<name sortKey="Shimazu, Hideki" sort="Shimazu, Hideki" uniqKey="Shimazu H" first="Hideki" last="Shimazu">Hideki Shimazu</name>
<name sortKey="Tamura, Tetsuya" sort="Tamura, Tetsuya" uniqKey="Tamura T" first="Tetsuya" last="Tamura">Tetsuya Tamura</name>
<name sortKey="Yamada, Kazumichi" sort="Yamada, Kazumichi" uniqKey="Yamada K" first="Kazumichi" last="Yamada">Kazumichi Yamada</name>
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